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KMID : 0882420120830060771
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Korean Journal of Medicine
2012 Volume.83 No. 6 p.771 ~ p.774
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A Case of Cholangiocarcinoma with Brain and Leptomeningeal Carcinomatosis
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Back Dae-Hyun
Yang Ki-Young
Lee Ye-Rim
Cho Su-Yeon
Lim Kyung Ah
Byun Jun-Su
Park Sun-Hoo
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Abstract
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Cholangiocarcinoma is a malignant disease originating from the epithelium of the biliary tract, and its prognosis is dismal due to distant metastasis in its early stages. The most common metastatic sites are the intra-abdominal organs, lymph nodes, and lungs. A patient was diagnosed with intrahepatic cholangiocarcinoma and underwent surgical resection. During the follow-up period, metastases were detected at the remnant liver and both lung fields. Eleven months after resection, the patient complained of severe headache. An approximately 5-cm cystic mass was found at the left occipital lobe of the cerebrum, and metastatic malignant cells were present on cerebrospinal fluid cytology. The patient underwent whole-brain radiotherapy. We herein report a rare case of cholangiocarcinoma with cystic brain metastasis together with a review of the relevant literature.
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KEYWORD
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Cholangiocarcinoma, Cystic mass, Brain metastasis, Leptomeningeal carcinomatosis
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